Virta Health Unveils Landmark Annual Report Defining a New Era of Metabolic Disease Reversal

New data reveals company’s AI-powered, individualized nutrition therapy reduces risk of heart attack, stroke, or death by 56% while also reversing Type 2 Diabetes and obesity; and saved $1 billion+ in healthcare costs

DENVER--(BUSINESS WIRE)--Virta Health, the leader in reversing metabolic disease, has released its inaugural Annual Report on Metabolic Disease Reversal. The report underscores a fundamental truth: the most powerful way to revolutionize healthcare and lower costs is not through disease management, but disease reversal, at scale.

Today, 93% of American adults show signs of poor metabolic health.¹ With the chronic conditions that follow driving an estimated $1-1.5 trillion of annual U.S. healthcare costs², Virta's findings arrive at a pivotal moment.

“For decades, metabolic disease has been treated by managing several separate conditions: obesity, type 2 diabetes, high blood pressure, cardiovascular disease, fatty liver, and more. But they’re not separate. They share a common root cause: poor nutrition,” said Sami Inkinen, Co-Founder and CEO of Virta Health. “You can’t fix a food problem with drugs. By addressing the root cause with individualized nutrition, you don’t have to manage chronic diseases, you reverse them. That’s not just theory and hope. Our Annual Report proves metabolic disease reversal is real, it’s measurable, and it’s happening today, at scale.”

The Metabolic Disease Revolution

The Annual Report serves as a living record of metabolic disease reversal, chronicling measurable and sustainable outcomes achieved through Virta’s AI-powered individualized nutrition therapy. The results based on hundreds of thousands of Virta members demonstrate transformation across populations, proving that metabolic disease reversal is not just possible, but equitable and scalable.

• Sustained, root-cause reversal outcomes: Members achieved durable improvements in metabolic health, measured across biomarkers and impressive end outcomes:
  • 56% reduced risk of heart attack, stroke, or death
  • 53-64% reduction in all-cause mortality
  • 33% lower risk of new chronic kidney disease diagnoses
  • 13% Sustained weight loss and 60% T2D reversal rate (as previously reported)
  • 75 million units of insulin eliminated, and 50% reduction of GLP-1 use while improving weight loss and diabetes outcomes

• System impact and rewriting the economics of health: Beyond individual transformation, Virta delivers system-wide impact, reducing utilization and cost across the ecosystem:
  • $1B+ saved in healthcare costs
  • $118 million in GLP-1 costs avoided

“The data in this report represents one of the most comprehensive views of metabolic disease reversal to date. A 56% reduction in risk for heart attack, stroke, or death and 53-64% reduction in all-cause mortality isn’t incremental progress, it’s proof that Virta’s AI-powered, individualized nutrition treatment is changing what’s possible in metabolic disease care,” said Dr. Adam Wolfberg, Chief Medical Officer at Virta Health.

By uniting metabolic conditions which were historically treated on symptom level silos, Virta members aren’t managing multiple diagnoses, they’re reversing one disease and gaining years back to their lives. McKinsey Health Institute reports promoting metabolic health could yield 3.5 times more healthy life years than addressing obesity alone, and pursuing metabolic health for all could lead to a $5.65 trillion annual GDP uplift in 2050.³

Having treated over 200,000+ members and counting, the Annual Report on Metabolic Disease Reversal proves that the best kind of disease management is actually disease reversal - from pounds lost and prescriptions eliminated to lives and dollars saved.

All outcome data referenced in this release are drawn from Virta Health’s Annual Report on Metabolic Disease Reversal (2025). Data includes results from peer-reviewed clinical trials conducted over varying study periods, Virta’s longitudinal program datasets spanning the past decade, and de-identified, aggregated real-world results from our active book of business and from a data clearinghouse. Each analysis is independently reviewed and validated by Virta’s data science and research teams to ensure methodological accuracy and consistency with findings.

For full methodology and definitions, visit https://www.virtahealth.com/reversal-report

To learn more about metabolic disease reversal, visit https://www.virtahealth.com/metabolic-disease

About Virta Health

Virta Health is a leader in reversing metabolic disease. Through their AI-powered individualized nutrition therapy, Virta combines the best of human care with the speed and precision of technology to empower members to build longer, healthier lives, while reducing or eliminating the need for medications. Virta partners with the nation’s largest employers, payers, and pharmacy benefit managers to improve the health of their members while reducing costs. Headquartered in Denver, Colorado, Virta is on a bold mission to reverse diabetes and obesity in one billion people. For more information, visit www.virtahealth.com.

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¹ttps://now.tufts.edu/2022/07/05/only-7-american-adults-have-good-cardiometabolic-health
²tps://www.virtahealth.com/reversal-report
³tps://www.mckinsey.com/mhi/our-insights/the-path-toward-a-metabolic-health-revolution