ZAP Surgical to Debut Its Groundbreaking ZAP-X® Gyroscopic Radiosurgery® Platform at ASTRO 2025

First Appearance at ASTRO Showcases Vault-Free, Cobalt-Free Innovation in Stereotactic Radiosurgery

SAN CARLOS, Calif.--(BUSINESS WIRE)--ZAP Surgical Systems, Inc., a global leader in non-invasive robotic brain surgery, today announced its debut at the 2025 ASTRO (American Society for Radiation Oncology) Annual Meeting, to be held September 28 – October 1 in San Francisco, California. ZAP Surgical will showcase the ZAP-X® Gyroscopic Radiosurgery® platform to the ASTRO community, alongside its internationally recognized, award-winning ZAP-Axon® Radiosurgery Planning System^*.

Attendees will have the opportunity to explore a near full-scale model of the ZAP-X system, a dedicated cranial radiosurgery (SRS) innovation that eliminates the need for costly radiation-shielded vaults and replaces outdated Cobalt-60 sources with advanced linear accelerator technology.

Live demonstrations of the ZAP-Axon planning software will also be available, offering a hands-on look at ZAP’s next-generation approach to stereotactic radiosurgery (SRS) planning.

“We are honored to bring ZAP-X to ASTRO for the first time,” said John R. Adler, MD, founder and CEO of ZAP Surgical, and Emeritus Dorothy & TK Chan Professor of Neurosurgery and Radiation Oncology at Stanford University. “With its dedicated cranial SRS design, ZAP-X empowers radiation oncologists to efficiently deliver the highest quality care without the compromises commonplace with multi-purpose radiation delivery systems.”

The ZAP-X system leverages gyroscopic mobility to deliver radiosurgical beams from thousands of unique angles, enhancing dose shaping and aiding the sparing of healthy brain tissue and critical structures. This high-precision approach not only helps reduce treatment-related risk but also aims to better preserve mental function in patients undergoing brain radiosurgery.

“Focusing solely on conformality and dose gradient in cranial radiosurgery is outdated thinking. Recent studies reveal that multi-purpose radiotherapy systems can expose significantly more healthy brain tissue to unnecessary radiation, which early evidence suggests may lead to deleterious effects such as neurocognitive decline,” said Dr. Adler. “That’s a profoundly important distinction. Emerging research confirms that even low doses to healthy brain tissue significantly changes brain function.”

Throughout ASTRO 2025, Dr. Adler and the ZAP Surgical team will host a series of in-booth presentations introducing the ZAP-X technology and its unique value proposition for modern radiation oncology practices.

To coordinate a VIP ZAP-X platform introduction or ZAP-Axon Radiosurgery Planning demonstration, please email [e-mail]. Or for additional general information, please visit www.zapsurgical.com.

* The ZAP-Axon Radiosurgery Planning System is pending US FDA 510(k) clearance and EU CE mark declaration.

About ZAP Surgical Systems, Inc.

ZAP Surgical Systems, Inc., a global leader in non-invasive robotic brain surgery, is committed to reducing the costs and complexities that limit access to world-class radiosurgery (SRS) for the brain, head, and neck. The company manufactures the ZAP-X® Gyroscopic Radiosurgery® platform and is also pioneering new applications of high-precision SRS in areas such as depression, addiction, and obesity. Founded in 2014 by Dr. John R. Adler, Emeritus Dorothy & TK Chan Professor of Neurosurgery and Radiation Oncology at Stanford University, ZAP introduced the world’s first vault-free radiosurgery platform - eliminating the need for costly shielded treatment rooms and enabling flexible, high-visibility siting. ZAP-X also advances beyond legacy Cobalt-60 technology with a modern linear accelerator for safer, more sustainable care. Learn more at ZAP Surgical and follow us on LinkedIn.