HydroPeptide Unveils Collagen ReActivate PM: A Groundbreaking Nighttime Treatment Rooted in 20 Years of Peptide Science

This first innovation in the new Collagen ReActivate collection leverages HydroPeptide’s patented NIMNI™ Technology, retinol, and regenerative peptides to transform skin overnight.

BELLEVUE, Wash.--(BUSINESS WIRE)--HydroPeptide, a pioneer in peptide science and regenerative skincare, is redefining nighttime skincare with the launch of Collagen ReActivate PM Lifting Treatment Moisturizer + Retinol. This next-generation formula is designed with collagen-optimizing NIMNI™ Technology, time-release retinol, and regenerative peptides to visibly lift, firm, and restore optimal skin health while you sleep.

The result of over two decades of clinical research, Collagen ReActivate PM was developed in collaboration with Dr. Marcel Nimni, a pioneer in the discovery of Type II collagen. This launch represents a major advancement in the company’s mission to support skin health at the cellular level and underscores its continued commitment to ingredient integrity, clinical efficacy, and exceptional user experience.

“Collagen ReActivate PM is a culmination of everything we stand for,” says Annette Rubin, CEO of HydroPeptide. “This formulation reflects decades of scientific discovery, our unwavering dedication to high-performing peptides, and our belief that clinical skincare should feel as incredible as it performs. More than a mere moisturizer, this is a next-generation solution designed to support skin regeneration during the body’s most crucial restorative period.”

Regenerative Technology Ahead of Its Time

Collagen ReActivate PM is the only treatment on the market formulated with NIMNI™ Technology. This proprietary blend of amino acids and antioxidants is clinically proven to optimize collagen production. By supporting this process in three key ways—strengthening and enhancing the skin’s structural integrity, feeding cells the nutrients they need to maintain healthy and abundant collagen, and signaling the skin to increase collagen production—NIMNI™ Technology is shown to increase collagen synthesis by 200% at 90 hours after application.

The Power of a Serum in a Luxurious Cream

Collagen ReActivate PM integrates NIMNI™ Technology with highly concentrated actives proven to transform skin. Time-release retinol (0.25%) enhances skin texture and tone while biomimetic peptides (SYN^®-TC and Neodermyl^®) and antioxidants (vitamin C and Ellagi-C™) work synergistically to improve firmness, reduce the look of fine lines, and brighten skin.

Clinically Proven Results

According to a study published in the Journal of Drugs in Dermatology:

• 91% saw fewer lines and wrinkles and improved texture
• 7 key signs of aging were visibly reduced, including wrinkles, skin sagging, and uneven skin tone

Clean, science-forward formulation

Like all HydroPeptide products, Collagen ReActivate PM is free of parabens, phthalates, sulfates, genotoxins, and harmful fragrance. The formula is vegan, gluten-free, not tested on animals, and has a skin-healthy pH of 6.9.

HydroPeptide continues to redefine skin health with formulas that improve skin's cellular function to deliver clinical-grade results that go beyond the surface. For more information, visit HydroPeptide.com.